Human Sera
Cayman Chemical EfInaconazole 100mg
A triazole antifungal agent; inhibits the growth of T. rubrum and T. mentagrophytes clinical isolates (MICs of ≤2 to 60 ng/ml) and of C. albicans clinical isolates (MICs of ≤0.5 to >250 ng/ml); inhibits sterol 14α-demethylase and arrests ergosterol biosynthesis at the fungal membrane; inhibits ergosterol biosynthesis in T. mentagrophytes and C. albicans with (IC50s = 7.0 and 0.40 ng/ml, respectfully)
Cayman Chemical SulconazolenItrate 50mg
An azole antifungal; active against dermatophyte fungal species, including isolates of various Candida species; non-specific inhibitor of styrene metabolism by cytochrome P450 (CYP450) enzymes; inhibits various CYP450 isoforms in human lymphoblast microsomes in vitro (Kis = 0.008-3.5 µM); inhibits heme oxygenase 1 activity in rat spleen microsomes (IC50 = 1.1 µM); inhibits DNA damage induced by styrene metabolism by bacterial CYP450cam (Ki = 204.2 μM)
Cayman Chemical ArsenobetaIn 50mg
An organoarsenical and compatible solute; protective against B. subtilis cell death induced by high osmolarity or extreme temperatures at 1 mM; non-toxic to mice (LD50 = 10 g/kg)
Cayman Chemical BendamustInhydrochlorIde 50mg
A DNA alkylating agent; inhibits growth of SKW-3, Reh, CML-T1, BV-173, and HL-60 leukemia cell lines (IC50s = 27.0, 28.6, 15.6, 20.8, and 57.7 μM, respectively) but not MCF-7 and MDA-MB-231 breast cancer cell lines (IC50s = >200 and >200 μM, respectively); kills B-CLL cells derived from naïve and bendamustine-pretreated patients (LD50s= 6.8-8.3 and 3.8-4.9 mg/ml, respectively); inhibits tumor growth by 9% and 96% alone and in combination with ofatumumab, respectively, in a JVM-3 CLL mouse xenograft model (50 mg/kg)
Cayman Chemical AcamprosatecalcIum salt 100mg
An NMDA modulator with antagonist or agonist effects depending on brain region, receptor composition, and other factors; an acetylated derivative of homotaurine; decreases paired-pulse inhibition of GABAA IPSCs, indicating that it may inhibit GABAB autoreceptor-mediated inhibition of GABA release (300 µM); reduces voluntary intake of ethanol in rats (0.26 and 0.52 mmol/kg per day, i.p.)
Cayman Chemical N-AcetylserotonIn 50mg
An analytical reference standard categorized as a tryptamine; a precursor in the synthesis of melatonin; intended for analytical forensic applications
Cayman Chemical ToltrazurIl sulfon 50mg
An active metabolite of toltrazuril; formed from toltrazuril via the intermediate metabolite toltrazuril sulfoxide by CYP enzymes, including CYP3A; inhibits T. gondii tachyzoite production in African green monkey kidney cells at 0.1, 1, and 5 UG/ml; completely prevents infection with T. gondii tachyzoites in a mouse model of fatal toxoplasmosis at 10 or 20 mg/kg one day prior to, and daily for 10 days following, infection; reduces the number of infected mice in the same model at 10 mg/kg for 11 days starting six days following infection
Cayman Chemical BalsalazIde 50mg
A prodrug form of 5-ASA; cleaved by bacterial azoreductases in the intestinal lumen to release 5-ASA; decreases IL-2 levels and increases IL-6 levels in the serum and colonic mucosa membrane, as well as decreases micro- and macroscopic colonic damage, in a rat model of DNCB-induced colitis at 600 mg/kg per day
Cayman Chemical Ac DArgCEH DPheRWCNH 50mg
An MC4R agonist; induces cAMP release in HEK293 cells expressing human MC4R (EC50 = 0.28 nM); is selective for MC4R over MC1R, MC3R, and MC5R (Kis = 0.55, 16.78, 56.79, and >500 nM, respectively); decreases food intake and body weight in a rat model of diet-induced obesity at 0.075 or 0.299 µmol/kg
Research Products International Corp Individual Cardboard Cover w/ Pop-Up Lid, 25/cs
Heavy Duty cardboard cover for use with Corrugated Radioactive Waste Box. Cover sits on top of Waste Box and features a Pop-Up Lid for convenience. Covers ship flat to prevent damage and need to be folded into final shape before use.
AdipoGen BioStab Antibody Stabilizer
Free or conjugated antibodies are often used in immunoassays, either in the system specific detector antibody plus streptavidin-HRP or in the system analyte-specific antibody plus species-specific antibody-HRP-conjugate. Both systems allow a high flexibility at lower costs. BioStab Antibody Stabilizer dramatically extends the life of your valuable antibodies, allowing much more consistent results over extended periods of time compared to daily prepared dilutions. BioStab Antibody Stabilizer can be used in ELISA, Western Blotting, Immunohistochemistry and any other applications which require marker or biotinylated antibodies. It is supplied as a ready-to-use solution for dilution of antibodies. This stabilizer contains a minimum amount of a surfactant. The stabilizer is free of any protein to minimize potential unspecific interactions. The method below is strongly recommended for standard assay procedures and reduces loss of valuable conjugates and assay-to-assay variations.
Cayman Chemical pIodoClonIdInhydrochLRI 50mg
A partial agonist of the α2-adrenergic receptor, minimally inhibiting adenylate cyclase through this Gi protein-coupled receptor although it binds avidly (Ki = 1.0 nM); potentiates platelet aggregation by ADP (EC50 = 1.5 µM) and inhibits epinephrine-induced aggregation (IC50 = 5.1 µM)